HEALTH EFFECTS Toxicological Profile For Uranium NCBI

Toxicological Profile for Uranium - PubMed

The information is taken from a toxicological profile developed by ATSDR’s Division of Toxicology and Human Health Sciences (DTHHS). A toxicological profile is a thorough review of a hazardous substance. This toxicological profile examines uranium. This public health statement summarizes the DTHHS findings on uranium, describes the effects of ...

USER'S GUIDE - Toxicological Profile for Uranium - NCBI ...

This chapter of the profile is a health effects summary written in non-technical language. Its intended audience is the general public, especially people living in the vicinity of a hazardous waste site or chemical release. If the Public Health Statement were removed from the rest of the document, it would still communicate to the lay public essential information about the chemical.

RELEVANCE TO PUBLIC HEALTH - Toxicological Profile for ...

Uranium is an alpha-emitting, radioactive, heavy metal that occurs naturally in nearly all rocks and soils. Twenty-two isotopic forms of uranium have been identified, mainly associated with nuclear reactor operations or high-energy physics experiments; the most prevalent isotopes found in the environment are the three naturally-occurring isotopes: 234U, 235U, and 238U. Most uranium …

ATSDR MINIMAL RISK LEVELS AND WORKSHEETS - Toxicological ...

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. Keith S, Faroon O, Roney N, et al. Toxicological Profile for Uranium. Atlanta (GA): Agency for Toxic Substances and Disease Registry (US); 2013 Feb.

Health effects of uranium: new research findings

With the potential for more uranium mining worldwide and a growth in the literature on the toxicology and epidemiology of uranium and uranium mining, we found it timely to review the current state of knowledge. Here, we present a review of the health effects of uranium mining, with an emphasis on newer findings (2005-2011).

Metals and health: a clinical toxicological perspective on ...

Although the toxicological profiles of all these metals are well known, their internalization as embedded shrapnel may be considered a new route for long-term exposure. Studies in experimental animals and cell culture indicate that pellets based on heavy metal tungsten alloy possess carcinogenic potential previously unseen for depleted uranium ...

Uranium | Toxicological Profile | ATSDR

The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the …

QUICK REFERENCE FOR HEALTH CARE PROVIDERS - Toxicological ...

Toxicological Profiles are a unique compilation of toxicological information on a given hazardous substance. Each profile reflects a comprehensive and extensive evaluation, summary, and interpretation of available toxicologic and epidemiologic information on a substance. Health care providers treating patients potentially exposed to hazardous substances will find the …

Toxicological Profile for Uranium - Agency for Toxic ...

human health of acute, subacute, and chronic health effects; and (C) Where appropriate, identifies toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans. The principal audiences for the toxicological profiles are federal, state, and local health professionals;

HEALTH EFFECTS - Toxicological Profile for Radon - NCBI ...

The bulk of health effects information for the mining cohorts reported in this toxicological profile for radon derives from the most recent analyses of pooled data from 11 mining cohorts (Lubin et al. 1997; NAS 1999a; NIH 1994) using the most recent and comprehensive follow-up results from available studies of individual mining cohorts.

Metals and health: a clinical toxicological perspective on ...

Although the toxicological profiles of all these metals are well known, their internalization as embedded shrapnel may be considered a new route for long-term exposure. Studies in experimental animals and cell culture indicate that pellets based on heavy metal tungsten alloy possess carcinogenic potential previously unseen for depleted uranium ...

TOXICOLOGICAL PROFILE FOR URANIUM

A Toxicology Profile for Uranium was released in September 1997. This edition supersedes any previously released draft or final profile. Toxicological profiles are revised and republished as necessary, but no less than once every three years. For information regarding the update status of previously released profiles, contact ATSDR at:

Toxicological profile for uranium. Final report (Technical ...

Dec 01, 1990· @article{osti_5611979, title = {Toxicological profile for uranium. Final report}, author = {}, abstractNote = {The ATSDR Toxicological Profile for Uranium is intended to characterize succinctly the toxicological and health effects information for the substance. It identifies and reviews the key literature that describes the substances's toxicological properties.

Uranium | Public Health Statement | ATSDR

The information is taken from a toxicological profile developed by ATSDR's Division of Toxicology and Human Health Sciences (DTHHS). A toxicological profile is a thorough review of a hazardous substance. This toxicological profile examines uranium. This public health statement summarizes the DTHHS findings on uranium, describes the effects of ...

TOXICOLOGICAL PROFILE FOR URANIUM

A Toxicology Profile for Uranium was released in September 1997. This edition supersedes any previously released draft or final profile. Toxicological profiles are revised and republished as necessary, but no less than once every three years. For information regarding the update status of previously released profiles, contact ATSDR at:

Public Health Statement for Uranium

PUBLIC HEALTH STATEMENT Uranium Division of Toxicology and Environmental Medicine September 2011 This Public Health Statement is the summary chapter from the Toxicological Profile for Uranium. It is one in a series of Public Health Statements about hazardous substances and their health effects. A shorter version, the ToxFAQs™, is also available.

TOXICOLOGICAL PROFILE FOR RADIUM

2. HEALTH EFFECTS 2.1 INTRODUCTION This chapter contains descriptions and evaluations of studies and interpretation of data on the health effects associated with exposure to radium. Its purpose is to present levels of significant exposure for radium based on toxicological studies, epidemiological investigations, and environmental exposure data.

Emerging health risks and underlying toxicological ...

Dec 01, 2020· There are 45 published review papers from 2000 to 2020 focusing on the correlation between uranium contamination and health risks (Table S1), which have promoted a deep understanding of uranium-induced health problems.Comparatively, less attention has been paid to the toxicological mechanisms of uranium because only 8 review papers were …

Toxicological Profile for Cadmium - pubmed.ncbi.nlm.nih.gov

Sep 02, 2020· This public health statement tells you about cadmium and the effects of exposure to it. The Environmental Protection Agency (EPA) identifies the most serious hazardous waste sites in the nation. These sites are then placed on the National Priorities List (NPL) and are targeted for long-term federal …

Toxicological Profile for Chromium - PubMed

This public health statement tells you about chromium and the effects of exposure to it. The Environmental Protection Agency (EPA) identifies the most serious hazardous waste sites in the nation. These sites are then placed on the National Priorities List …

Toxicological Profile for Uranium

Apr 05, 2021· The Agency for Toxic Substances Disease Registry Toxicological Profile succinctly characterizes toxicological and adverse health effects information for uranium. The focus of this profile is on health and toxicological information and therefore begins with a Public Health Statement that summarizes in non-technical language, uranium's relevant ...

Uranium) Radionuclides (including Radon, Radium and

Substances and Disease Registry's (ATSDR's) Toxicological Profiles for Uranium, Radium, and Radon. (1) Uses Uranium is used in nuclear power plants and nuclear weapons. Very small amounts are used in photography for toning, in the leather and wood industries for stains and dyes, and in the silk and wood industries. (2)

Appendix A. Background Information for Uranium

uranium isotopes are expected, and the kinetics of distribution of the emitted radiation, which has a very short path length, can be predicted based on the pharmacokinetic parameters of stable uranium. A.2 . Health Effects . Absorbed uranium is nephrotoxic. Clinical case studies indicate that uranium can produce nephrotoxic

Toxicological Profile for Thorium

ATSDR’s Toxicological Profile for Thorium was released in 1990. In order to update the literature in this profile, ATSDR conducted a literature search focused on health effects information as described in Appendix B. Chapters 2 and 3 were revised to reflect the most current health effects data. In some cases,

Uranium | Public Health Statement | ATSDR

The information is taken from a toxicological profile developed by ATSDR's Division of Toxicology and Human Health Sciences (DTHHS). A toxicological profile is a thorough review of a hazardous substance. This toxicological profile examines uranium. This public health statement summarizes the DTHHS findings on uranium, describes the effects of ...

Toxicological profile for uranium. Final report (Technical ...

Dec 01, 1990· @article{osti_5611979, title = {Toxicological profile for uranium. Final report}, author = {}, abstractNote = {The ATSDR Toxicological Profile for Uranium is intended to characterize succinctly the toxicological and health effects information for the substance. It identifies and reviews the key literature that describes the substances's toxicological properties.

Toxicological Profile for Uranium

Apr 05, 2021· The Agency for Toxic Substances Disease Registry Toxicological Profile succinctly characterizes toxicological and adverse health effects information for uranium. The focus of this profile is on health and toxicological information and therefore begins with a Public Health Statement that summarizes in non-technical language, uranium's relevant ...

Uranium) Radionuclides (including Radon, Radium and

Substances and Disease Registry's (ATSDR's) Toxicological Profiles for Uranium, Radium, and Radon. (1) Uses Uranium is used in nuclear power plants and nuclear weapons. Very small amounts are used in photography for toning, in the leather and wood industries for stains and dyes, and in the silk and wood industries. (2)

CONSIDERING A NONCANCER ORAL REFERENCE DOSE FOR …

and chronic health effects; and (C) Where appropriate, identifies toxicologic testing needed to identify the types or levels ofexposure that may present significant risk ofadverse health effects in humans. The principal audiences for the toxicological profiles are federal, state, and local health professionals; interested

Emerging health risks and underlying toxicological ...

Dec 01, 2020· There are 45 published review papers from 2000 to 2020 focusing on the correlation between uranium contamination and health risks (Table S1), which have promoted a deep understanding of uranium-induced health problems.Comparatively, less attention has been paid to the toxicological mechanisms of uranium because only 8 review papers were …

Health Effects and Environmental Justice Concerns of ...

Nov 04, 2016· Several previous reviews have cataloged the health effects associated with uranium exposure based on both toxicologic and epidemiologic evidence [13, 19–22].Additionally, the Agency for Toxic Substances and Disease Registry (ATSDR) toxicological profile for uranium was recently updated [3•].Therefore, our goal is not to …

Health Effects of Naturally Radioactive Water Ingestion ...

Dec 01, 2011· Renal effects of uranium in drinking water. Environ Health Perspect 110:337-342 11940450. Link, Google Scholar; Kurttio P, Harmoinen A, Saha H, Salonen L, Karpas Z, Komulainen H et al.. 2006a. Kidney toxicity of ingested uranium from drinking water. Am J Kidney Dis 47(6):972-982 16731292. Crossref, Medline, Google Scholar

Depleted Uranium: Technical Brief

internalized, will all aled to adverse health effects similar to those of other tals heavy me such as lead and cadium. The Agency for m Toxic Substances and Diseas Registry es (ATSDR) Toxicological Profile on uranium [1] summarizes the existing animal and human data on the toxicology of natural uranium.

Toxicological Profile for Manganese - PubMed

This public health statement tells you about manganese and the effects of exposure to it. The Environmental Protection Agency (EPA) identifies the most serious hazardous waste sites in the nation. These sites are then placed on the National Priorities List …

Report on the Health Impacts of Proposed Uranium Mining ...

Public Health Impacts of Uranium Mining (Nov. 17, 2011) 3 IV. DIRECT HEALTH IMPACTS OF URANIUM MINING 1. Greater Exposure. Peer-reviewed research and government reports confirm that populations living near uranium mines or mills may be exposed to higher levels of uranium in drinking water and locally grown foods due to

Uranyl sulfate | UO2SO4 - PubChem

Approximately 60% of uranium absorbed into the blood is transported in the form of a bicarbonate complex, and 40% is bound to plasma proteins. The uranyl-bicarbonate complex is filtered out of the blood by the renal glomerulus and is passed into the tubules.The pH of urine decreases in the tubules, resulting in dissociation of the complex and release of the reactive …

(PDF) Toxicological aspects of depleted uranium

Toxicological aspects of depleted uranium. ... Profile for Uranium, ... Committed effective doses over 50 years are related to the stochastic health effects …

TOXICOLOGICAL PROFILE FOR PLUTONIUM

2. HEALTH EFFECTS 2.1 INTRODUCTION This chapter contains descriptions and evaluations of studies and interpretation of data on the health effects associated with exposure to plutonium. Its purpose is to present levels of significant exposure to plutonium based on toxicological studies, epidemiological investigations, and environmental exposure ...